學歷  

中興大學  分子生物所  博士

台灣大學  微生物學所  碩士  

中山醫學院 醫事技術系  學士  

專長　 

微生物學、分子生物學、臨床微生物學、蛋白質化學

任教科目  

微生物學、臨床微生物檢驗學、蛋白質工程、臨床病毒學

研究成果

(A) 期刊論文

Hsueh-Hsia Lo, Chao-Tsai Liao, Chih-En Li, Ying-Chuan Chiang, Yi-Min Hsiao* (2020) The clpX gene plays an important role in bacterial attachment, stress tolerance, and virulence in Xanthomonas campestris pv. campestris. Archives of Microbiology 202:597-607. (SCI)

Jui-Shan Ma, Sin-Yu Chen, Hsueh-Hsia Lo^* (2017) Biofilm formation of beta-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis isolates and its association with emm polymorphism. APMIS 125:1027-1032. (SCI) (corresponding author)

Chao-Tsai Liao, Hsueh-Hsia Lo, Weng-Ting Peng, Wan-Ling Song, Shin-Chiao Du, Yi-Min Hsiao^* (2017) XCC2366, a gene encoding a putative TetR family transcriptional regulator, is required for acriflavin resistance and virulence of Xanthomonas campestris pv. campestris. Current Microbiology 74:1373-1381. (SCI)

Chao-Tsai Liao, Yu-Fan Liu, Ying-Chuan Chiang, Hsueh-Hsia Lo, Shin-Chiao Du, Pei-Chi Hsu, Yi-Min Hsiao^* (2016) Functional characterization and transcriptome analysis reveal multiple roles for prc in the pathogenicity of the black rot pathogen Xanthomonas campestris pv. campestris. Research in Microbiology 167:299-312. (SCI)

Sue-Er Hsieh, Yi-Hsiung Tseng, Hsueh-Hsia Lo, Shui-Tu Chen, Cheng-Nan Wu^* (2016) Genomic analysis of Staphylococcus phage Stau2 isolated from medical specimen. Virus Genes 52:107-116. (SCI)

Hsueh-Hsia Lo^*, Wei-Shan Chen (2015) Distribution of virulence factors and association with emm polymorphism or isolation site among beta-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis. APMIS 123:45-52. (SCI) (corresponding author)

Yi-Cheng Chang, Hsueh-Hsia Lo^*, Hsiu-Ying Hsieh, Shan-Min Chang (2015) Identification, epidemiological relatedness, and biofilm formation of clinical Chryseobacterium indologenes isolates from central Taiwan. Journal of Microbiology, Immunology and Infection 48:559-564. (SCI) (corresponding author)

Hsueh-Hsia Lo^*, Hao-Hsiang Nien, Ya-Yu Cheng, and Fang-Yi Su (2015) Antibiotic susceptibility pattern and erythromycin resistance mechanisms in beta-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis isolates from central Taiwan. Journal of Microbiology, Immunology and Infection 48:613-617. (SCI) (corresponding author)

Hsueh-Hsia Lo^*, Wei-Shan Chen (2014) Distribution of virulence factors and association with emm polymorphism or isolation site among beta-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis. APMIS (accepted) (SCI) (corresponding author) (NSC 99－2320－B－166－002－MY3)

Hsueh-Hsia Lo^*, Hao-Hsiang Nien, Ya-Yu Cheng, and Fang-Yi Su (2014) Antibiotic susceptibility pattern and erythromycin resistance mechanisms in beta-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis isolates from central Taiwan. Journal of Microbiology, Immunology and Infection http://dx.doi.org/10.1016/j.jmii.2014.04.003 (SCI) (corresponding author) (NSC 99－2320－B－166－002－MY3 and NSC101－2815－C－166－005-B)

Yi-Cheng Chang, Hsueh-Hsia Lo^*, Hsiu-Ying Hsieh, Shan-Min Chang (2014) Identification, epidemiological relatedness, and biofilm formation of clinical Chryseobacterium indologenes isolates from central Taiwan. Journal of Microbiology, Immunology and Infection http://dx.doi.org/10.1016/j.jmii.2014.04.004  (SCI) (corresponding author) (FYH1011603-1 and Fong-Yuan Hospital 101-009)

Hsueh-Hsia Lo^*, Shan-Min Chang (2014) Identification, characterization, and biofilm formation of clinical Chryseobacterium gleum isolates. Diagnostic Microbiology and Infectious Disease 79:298-302.  (SCI) (corresponding author) (FYH1011603-1)

Chao-Tsai Liao, Shin-Chiao Du, Hsueh-Hsia Lo, Yi-Min Hsiao^* (2014) The galU gene of Xanthomonas campestris pv. campestris is involved in bacterial attachment, cell motility, polysaccharide synthesis, virulence, and tolerance to various stresses. Archives Microbiology 196:729-738. (SCI)

Yi-Cheng Chang, Hsueh-Hsia Lo^*, Hsiu-Ying Hsieh, Shan-Min Chang (2014) Identification and epidemiological relatedness of clinical Elizabethkingia meningoseptica isolates from central Taiwan. Journal of Microbiology, Immunology and Infection 47(4):318-23. (SCI) (corresponding author)

Yi-Cheng Chang, Hsueh-Hsia Lo^* (2013) Identification, clinical aspects, susceptibility pattern and molecular epidemiology of beta-haemolytic group G Streptococcus anginosus group isolates from central Taiwan. Diagnostic Microbiology and Infectious Disease 76:262-265. (SCI) (corresponding author) (FYH1000305-100.03 and Fong-Yuan Hospital 99-023 )

Yi-Cheng Chang, Hsueh-Hsia Lo^*, Hsiu-Ying Hsieh, Shan-Min Chang (2013) Identification and epidemiological relatedness of clinical Elizabethkingia meningoseptica isolates from central Taiwan. Journal of Microbiology, Immunology and Infection http://dx.doi.org/10.1016/j.jmii.2013.03.007 (SCI) (corresponding author) (Fong-Yuan Hospital 100-005)

Chien-Te Li, Chao-Tsai Liao, Shin-Chiao Du, Yu-Ping Hsiao, Hsueh-Hsia Lo, Yi-Min Hsiao^* (2013) Functional characterization and transcriptional analysis of galE gene encoding a UDP-galactose 4-epimerase in Xanthomonas campestris pv. campestris. Microbiological Research 169:441-452. (SCI)

Jen-Sheng Pei, Yi-Min Lee, Hseuh-Hsia Lo, Yuan-Nian Hsu, Song-Shei Lin^*, Da-Tian Bau^* (2013) Association of X-ray repair cross-complementing-6 genotypes with childhood leukemia. Anticancer Research 33:5395-5399. (SCI)

Yu-Fan Liu, Chao-Tsai Liao, Wan-Ling Song, Pei-Chi Hsu, Shin-Chiao Du, Hsueh-Hsia Lo and Yi-Min Hsiao^* (2013) GsmR, a response regulator with an HD-related output domain in Xanthomonas campestris, is positively controlled by Clp and is involved in the expression of genes responsible for flagellum synthesis. FEBS Journal 280:199-213. (SCI)

Sue-Er Hsieh, Hsueh-Hsia Lo, Shui-Tu Chen, Mong-Chuan Lee, and Yi-Hsiung Tseng^* (2011) Wide host range and strong lytic activity of Staphylococcus aureus lytic phage Stau2. Applied and Environmental Microbiology 77:756-761. (SCI)

Chin-Fu Lin, Shih-Kuang Hsu, Chao-Hsien Chen, Jr-Rung Huang, and Hsueh-Hsia Lo^* (2010) Genotypic detection and molecular epidemiology of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in a regional hospital in central Taiwan. Journal of Medical Microbiology 59:665-671. (SCI) (corresponding author) (EDU-0980055254-n)

Ling-ling Hsieh, Chen-Yu Chang Huey-Lih Shyu, Chi-An Tsou, and Hsueh-Hsia Lo^* (2010) The inhibition effect of TiO₂/Ag thin film on Acinetobacter baumannii. Advanced Materials Research Vols. 123-125 pp 272-275. (EI) (corresponding author)

Chen-Yu Chang, Shih-Kuang Hsu, Chen-Jung Chang, Yaw-Nan Shieh , Ching-Lan Chang, and Hsueh-Hsia Lo^* (2010) The effect of visible light-activated TiO₂ thin film on nosocomial pathogens. Advanced Materials Research Vols. 123-125 pp 268-271 (EI) (corresponding author)

Kai-Yuan Cheng, Kuo-Shan Yao, Hsueh-Hsia Lo, Chen-Yu Chang^* and Po-Hsiang Chen (2010) Photoelectrocatalytic degradation of isopropyl alcohol by TiO₂/Ti thin-film electrode. Advanced Materials Research Vols. 123-125 pp 165-168. (EI)

Hsueh-Hsia Lo, Wei-De Lin, Shih-Kuang Hsu, and Wen-Hwei Hsu^* (2009) Asymmetrically simultaneous synthesis of L-Homophenylalanine and N⁶-Protected-2-oxo-6-amino-hexanoic acid by engineered Escherichia coli aspartate aminotransferase. Biotechnology Progress 25(6):1637-1642. (SCI) (NSC 95-2313-B-166-010-MY3)

Chao-Hung Kao, Hsueh-Hsia Lo, Shih-Kuang Hsu, Wen-Hwei Hsu^* (2008) A novel hydantoinase process using recombinant Escherichia coli cells with dihydropyrimidinase and L-N-carbamoylase activities as biocatalyst for the production of L-homophenylalanine. Journal of Biotechnology 134:231-239. (SCI)

Shih-Kuang Hsu, Hsueh-Hsia Lo, Wei-De Lin, I-Chieh Chen, Chao-Hung Kao, Wen-Hwei Hsu^* (2007) Stereoselective synthesis of L-homophenylalanine using the carbamoylase method with in situ racemization via N-acylamino acid racemase. Process Biochemistry 42:856-862. (SCI)

Shih-Kuang Hsu, Hsueh-Hsia Lo, Chao-Hung Kao, Dong-Sheng Lee, and Wen-Hwei Hsu^* (2006) Enantioselective synthesis of L-homophenylalanine by whole cells of recombinant Escherichia coli expressing L-aminoacylase and N-acylamino acid racemase genes from Deinococcus radiodurans BCRC 12827. Biotechnology Progress 22:1578-1584. (SCI)

Hsueh-Hsia Lo, Shih-Kuang Hsu, Wei-De Lin, Nei-Li Chan, and Wen-Hwei Hsu^* (2005) Asymmetrically synthesis of L-homophenylalanine using engineered Escherichia coli aspartate aminotransferase. Biotechnology Progress 21:411-415. (SCI)

Shih-Kuang Hsu, Long-Liu Lin, Hsueh-Hsia Lo and Wen-Hwei Hsu^* (2004) Mutational analysis of feedback inhibition and catalytic sites of prephenate dehydratase from Corynebacterium glutamicum. Archives of Microbiology 181:237-244. (SCI)

Hsueh-Hsia Lo, Chao-Hung Kao, Dong-Sheng Lee, Teng-Kuei Yang and Wen-Hwei Hsu^* (2003) Enantioselective synthesis of (S)-2-amino-4-phenylbutanoic acid by the hydantoinase method. Chirality 15:699-702. (SCI)

Hsueh-Hsia Lo^* and Jing-Gung Chung (1999) The effects of plant phenolics caffeic acid, chlorogenic acid and ferulic acid on arylamine N-acetyltransferase activities in human gastrointestinal microflora. Anticancer Research 19:133-139. (SCI) (corresponding author)

Hsueh-Hsia Lo^*, Sue-Er Hsieh, Kan-Jen Tsai, and Jing-Gung Chung (1999) The effect of ellagic acid on arylamine N-acetyltransferase activity in the bacterium Pseudomonas aeruginosa. Drug and Chemical Toxicology 22:555-562. (SCI) (corresponding author)

Jing-Gung Chung, Lii-Tzu Wu, Shih-Hsien Chang, Hsueh-Hsia Lo, Sue-Er Hsieh, Ying-Ching Li, and Chi-Fu Hung (1999) Inhibitory actions of berberine on arylamine N-acetyltransferase activity in strains of Helicobacter pylori from peptic ulcer patients. International Journal of Toxicology. 18:35-40. (SCI)

Hsueh-Hsia Lo^*, Sue-Er Hsieh, and Jing-Gung Chung (1998) The effect of sulindac on arylamine N-acetyltransferase activity in Pseudomonas aeruginosa. Microbios 93:159-168. ( corresponding author)

Sue-Er Hsieh, Hsueh-Hsia Lo, and Jing-Gung Chung (1998) The characteristics of arylamine N-acetyltransferase in Pseudomonas aeruginosa. Current Microbiology 36:353-360. (SCI)

Jing-Gung Chung, Mei-Fen Tsou, Hwang-Huei Wang, Hsueh-Hsia Lo, Sue-Er Hsieh,  Yee-Sang Yen, Li-Tzu Wu, Shih-Hsien Chang, Chin-Chin Ho, and Chi-Fu Hung (1998) Rhein affects arylamine N-acetyltransferase activity in Helicobacter pylori from peptic ulcer patients. Journal of Applied Toxicology 18:117-123. (SCI)

Hsueh-Hsia Lo^*, Yee-Sang Yen, Sue-Er Hsieh, and Jing-Gung Chung (1997) Glycyrrhizic acid inhibits arylamine N-acetyltransferase activity in Klebsiella pneumoniae in vitro. Journal of Applied Toxicology 17:385-390. (SCI) ( corresponding author)

Hsueh-Hsia Lo^*, Sue-Er Hsieh, and Jing-Gung Chung (1997) Nonsteroidal antiinflammatory drugs inhibit arylamine N-acetyltransferase activities of human gastrointestinal microflora in vitro. Journal of Biomedical ＆ Laboratory Sciences 9:61-67. ( corresponding author)

Sue-Er Hsieh, Hsueh-Hsia Lo, Yee-Sang Yen, and Jing-Gung Chung (1997) The effect of vitamin C on N-acetyltransferase activity in Klebsiella pneumoniae. Food and Chemical Toxicology 35:1151-1157. (SCI)

Jing-Gung Chung, Hsueh-Hsia Lo, Sue-Er Hsieh, and Yee-Sang Yen (1997) Ibuprofen inhibits arylamine N-acetyltransferase activity in the bacteria Klebsiella pneumoniae. Current Microbiology 35:195-200. (SCI)

Jing-Gung Chung, Hwang-Huei Wang, Mei-Fen Tsou, Sue-Er Hsieh, Hsueh-Hsia Lo, Yee-Sang Yen, Shih-Hsien Chang, Li-Tzu Wu, Jau-Hung Lee, and Chi-Fu Hung (1997) Evidence for arylamine N-acetyltransferase activity in the bacterium Helicobacter pylori. Toxicology Letters 91:63-71. (SCI)

(B) 研討會論文

羅雪霞^*,程微珊,陳心妤 Distribution of virulence factors and emm typing among β-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis isolates from central Taiwan (2013) 台灣微生物學會年會 (台北)

羅雪霞^*,陳心妤Streptococcus dysgalactiae subsp. equisimilis臨床分離株生物膜形成與emm型之相關性  (2013) 台灣微生物學會年會 (台北)

羅雪霞^*,粘皓翔,鄭雅瑜 中臺灣β-溶血G群Streptococcus dysgalactiae subsp. equisimilis分離株之藥物感受性型式及抗藥基因分析 (2012) 台灣微生物學會年會 (台南)

張一誠,謝秀英,張善閔,劉佩柔,吳孟芸,羅雪霞^* 中臺灣Chryseobacterium indologenes及 Chryseobacterium gleum分離株之分子鑑定、藥物感受型式、分子流行病學及生物膜形成探討  (2012) 台灣微生物學會年會 (台南)

羅雪霞^*,程微珊,張善閔,粘皓翔 中台灣Streptococcus dysgalactiae subsp. equisimilis臨床分離株毒力因子的偵測 (2011) 台灣微生物學會年會 (台南)

張一誠,張善閔,謝秀英,廖士傑,陳佩琦,羅雪霞^*中台灣Elizabethkingia meningoseptica 臨床分離株之分子鑑定與藥敏分析 (2011) 台灣微生物學會年會 (台南)

羅雪霞^*,廖朝財,張善閔,鄭雅瑜,張嘉志  利用16S rDNA定序鑑定台灣中部地區Elizabethkingia meningoseptica分離株 (2010) 台灣微生物學會年會 (台北)

   Ling-Ling Hsieh, Chen-Yu Chang, Huey-Lih Shyu, Chi-An Tsou and Hsueh-Hsia Lo^*   The Inhibition Effect of TiO₂/Ag Thin Film on Acinetobacter baumannii. (2010) The 3^rd International Conference on Multi-Functional Materials and Structures (Jeonju, Korea)

Chen-Yu Chang, Shih-Kuang Hsu, Chen-Jung Chang, Yaw-Nan Shieh, Ching-Lan Chang and Hsueh-Hsia Lo^*  The Effect of Visible Light-activated TiO₂ Thin Film on Nosocomial Pathogens. (2010) The 3^rd International Conference on Multi-Functional Materials and Structures (Jeonju, Korea)

Kai-Yuan Cheng, Kuo-Shan Yao, Hsueh-Hsia Lo, Chen-Yu Chang^* and Po-Hsiang Chen  Photoelectrocatalytic Degradation of Isopropyl Alcohol by TiO₂/Ti Thin-film Electrode.  (2010) The 3^rd International Conference on Multi-Functional Materials and Structures (Jeonju, Korea)

羅雪霞^*, 廖朝財, 張善閔, 鄭雅瑜 台灣中部某一區域醫院Elizabethkingia meningoseptica分離株的生化特性及分子鑑定 (2009) 台灣微生物學會年會 (台北)

羅雪霞^*, 張善閔, 許荻靈, 張嘉志, 蘇芳儀 台灣中部地區G群鏈球菌臨床分離株藥物感受性之分析 (2009) 台灣微生物學會年會 (台北)

Hsueh-Hsia Lo^*, Chen-Fu Lin, and Ching-Yi Lee  Outer Membrane Protein D Gene Mutation in Clinical Pseudomonas aeruginosa Isolates with Imipenem Resistant and Meropenem Susceptible Phenotype. (2008) 第十一屆西太平洋區化療及感染症會議(11th WPCCID, 台北) (傑出海報獎)

羅雪霞,許荻靈^*,蘇芳儀,黃芝蓉,李宜蓁 台灣中部某一區域醫院臨床分離之G群鏈球菌菌株的生化特性、分生技術鑑定、及流行病學調查 (2008) 台灣醫檢學會年會 (台北)

李靜宜,羅雪霞^*,林進福,陳昭賢  對Carbapenem感受性表現型不一致之綠膿桿菌菌株外膜蛋白OprD之表現 (2007) 台灣微生物學會年會 (台北)

Hsueh-Hsia Lo^*,Chen-Fu Lin,Chin-Tun Hung,Ching-Yi Lee,Ju-Wen Yang, and Ji-Rung Huang Survey of Carbapenem Resistence in Pseudomonas aeruginosa Isolates in a Central Taiwan Medical Center. (2006) 台灣微生物學會年會 (台北)

Shih-Kuang Hsu,Hsueh-Hsia Lo,I-Chieh Chen,Wen-Ching Wang,Wei-Chun Chiu, and Wen-Hwei Hsu. Characterization of N-acylamino Acid Racemase from Deinococcus radiodurans and Use of Racemase and Acylase in the Production of L-Homophenylalanine. (2005) 生物催化暨生物技術國際研討會(台中)

(C) 專利

專利：動態共培養系統 中華民國專利新型第 M 333416 號 2008.6.1-2017.11.6 專利權人：張振榮  創作人：張振榮, 嚴月秀, 呂春美, 許世光, 羅雪霞, 謝玲鈴, 林錫楨, 廖龍泉, 龔瑞英, 吳惠琪

專利：骨質密度檢測參考輔具 中華民國專利新型第 M 384639 號 2010.7.21-2020.2.24專利權人：張振榮  創作人：張振榮, 徐惠麗, 羅雪霞, 謝玲鈴, 許世光, 嚴月秀, 黃文濤, 林錫楨, 吳杰, 許筑翔

專利：齒槽骨攝影輔助夾具  中華民國專利新型第 M 389525 號 2010.10. 1-2020.1.7 專利權人：張振榮  創作人：張振榮, 徐惠麗, 羅雪霞, 謝玲鈴, 林錫楨, 許世光, 嚴月秀, 吳杰, 許筑翔