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黃慶三

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黃慶三 教授

 

 

專長: 科學論文習作，醫研專題討論

任教科目: 科學論文習作，專題研究

研究領域: 1. 遺傳性黃疸症 2. 基因多型性對於藥物療效和副作用之影響

  

 

研究方向:

有關藥物代謝每一種基因都將依據其檢測結果分為幾種組合型，並分析那些基因組合型是治療無效和引起副作用的先天因素 。吾等的長期目標，是期望建立實用之藥物基因篩檢法，在治療前就可預測療效不良和可能發生藥害的危險患者，以做為調整劑量或避免使用該藥的重要參考 。吾等的努力，將讓藥物基因學(亦即個人醫學)落實於服用藥物的台灣患者身上 。  

 

∴著作∵

期刊論文 (since 2004)

    1. Huang MJ, Kua KE, Teng HC, Tang KS, Weng HW, Huang CS*: Risk factors for severe hyperbilirubinemia in neonates. Pediatr Res 2004; 56: 682-689 (SCI).
    2. Hsieh TJ, Wu YC, Chen SC, Huang CS, Chen CY: Chemical constituents from Annona glabra. J Chin Chem Soc 2004; 51: 869-876 (SCI).
    3. Chen YL , Wang YC , Tang KS , Huang CS*: Variant UDP-glucuronosyltransferase 2B genes in Taiwanese. J Biomed Lab Sci 2004; 16: 31-38.
    4. Huang MJ, Yang SS, Lin MS, Huang CS*: Polymorphisms of the UDP- glucuronosyltransferase 1A7 gene in Taiwan Chinese. World J Gastroenterol 2005; 11: 797-802 (SCI).
    5. Huang CS, Huang MJ, Lin MS, Yang SS, Teng HC, Tang KS: Genetic factors related to unconjugated hyperbilirubinemia amongst adults. Pharmacogenetics & Genomics 2005; 15: 43-50 (SCI).
    6. Huang MJ, Chen YL, Chang CY, Huang YY, Huang CS*: Polymorphisms of the gene encoding multidrug resistance protein 1 in Taiwanese. J Food Drug Anal 2005; 13: 112-117. (SCI). 
    7. Tang KS, Chiu HH, Chen HH, Eng HL, Tsai CJ, Teng HC, Huang CS*: Link between colorectal cancer and polymorphisms in the uridine-diphospho- glucuronosyltransferase 1A7 and 1A1 genes. World J Gastroenterol 2005; 11: 3250-3254 (SCI).
    8. Tseng CS, Tang KS, Lo HW, Ker CG, Teng HC, Huang CS*: UDP-glucuronosyltransferase 1A7 genetic polymorphisms are associated with hepatocellular carcinoma risk and onset age. Am J Gastroenterol 2005; 100: 1758-1763 (SCI).
    9. Huang CS: Molecular genetics of unconjugated hyperbilirubinemia in Taiwanese. J Biomed Sci 2005; 12: 445-450 (SCI).
    10. Huang YY, Yang SS, Lin MS, Huang MJ, Huang CS*: The effects of variant UDP-glucuronosyltransferase 1A1 gene, glucose-6-phosphate dehydrogenase deficiency and thalassemia on cholelithiasis. World J Gastroenterol 2005; 11: 5710-5713 (SCI).
    11. Huang CS, Tan N, Yang SS, Sung YC, Huang MJ: Three variations of UDP- glucuronosyltransferase 1A1 gene cause Crigler-Najjar syndrome type 2. J Formos Med Assoc 2006; 105: 950-953 (SCI).
    12. Teng HC, Huang MJ, Tang KS, Yang SS, Tseng CS, Huang CS*: Combined UGT1A1 and UGT1A7 variant alleles are associated with increased risk of Gilbert’s syndrome in Taiwanese adults. Clin Genet 2007; 72: 321-328 (SCI).
    13. Tang KS, Lee CM, Teng HC, Huang MJ, Huang CS*: UDP-glucuronosyl- transferase 1A7 polymorphisms are associated with liver cirrhosis. Biochem Biophys Res Commun 2008; 366: 643-648. (SCI).
    14. Chao YC, Huang CS, Lee CN, Chang SY, King CC, Kao CN: Higher infection of dengue virus serotype 2 in human monocytes of patients with G6PD deficiency. PLoS ONE 2008; 3(2): e1557. doi:10.1371/journal.pone.0001557.
    15. Huang YY, Huang MJ, Yang SS, Teng HC, Huang CS*: Variations in the UDP- glucuronosyltransferase 1A1 gene for the development of unconjugated hyperbilirubinemia in Taiwanese. Pharmacogenomics 2008; 9: 1229-1235 (SCI).

 

*Corresponding author

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